CAF Confederation Cup Quarter-finals: Key Matches You Can’t Miss

The 2025/26 TotalEnergies CAF Confederation Cup enters a decisive stage this weekend as the quarter-final first-leg matches kick off, setting the tone for a series of high-stakes encounters across Africa.

Several thrilling clashes will capture the spotlight in mid-March, including a Moroccan derby and intense North African matchups that promise fierce battles for semi-final spots.

One of the most anticipated ties features Moroccan rivals Olympique Club de Safi and Wydad AC. The first leg takes place in Safi on 15 March at 22:00 GMT, with the return leg scheduled for 22 March in Casablanca at 19:00 GMT. This fixture guarantees that at least one Moroccan club will advance to the semi-finals.

Another key matchup sees Egyptian club Al Masry SC face Algeria’s CR Belouizdad. Their first-leg meeting is set for 14 March at 20:00 GMT, with the second leg a week later on 21 March at 19:00 GMT.

Egyptian giants Zamalek SC will begin their quarter-final campaign away from home against Congolese side AS Otoho on 14 March at 13:00 GMT, with the return leg slated for 22 March at 16:00 GMT.

In another exciting contest, DR Congo’s AS Maniema Union will host Algeria’s USM Alger for the first leg on 15 March at 13:00 GMT, before the second leg takes place in Algeria on 22 March at 19:00 GMT.

Fans can expect these quarter-finals to deliver tactical battles, high drama, and decisive moments as Africa’s top clubs compete for a place in the CAF Confederation Cup semi-finals.