The French Football Federation has confirmed that Dayot Upamecano has left the France squad for personal reasons, after reaching an agreement with manager Zinedine Zidane.
The Bayern Munich defender featured for France in their Nations League match against Italy.
Italy claimed a 3-1 victory over France in the fifth round of Group A, with the match played at San Siro.
The result moved Italy to 10 points, level with France, although Italy hold the advantage on goal difference. Belgium are second in the group with nine points, while Turkey sit bottom without a point after losing all five of their matches.
Italy will face Belgium in the final round of fixtures, while France will play Turkey on Sunday, 15 November.
