Al Nassr, featuring Senegalese international Sadio Mané, were held to a goalless draw by Iranian side Esteghlal in the first leg of the Asian Champions League round of 16.
The encounter, played in Iran, ended 0-0 as both teams struggled to break the deadlock in a tightly contested match.
Despite Al Nassr’s dominance in possession, Esteghlal’s resolute defence proved difficult to breach.
Mané was a lively presence in attack but was unable to capitalise on the opportunities that fell his way.
The former Liverpool forward consistently tested the opposition defence but lacked the finishing touch to put his side ahead.
Difficult playing conditions and a determined Esteghlal defence frustrated the visitors, who will now look to make home advantage count in the second leg in Saudi Arabia.
Al Nassr must improve their attacking efficiency if they hope to secure a place in the quarter-finals.
The return leg promises to be a decisive fixture, with both sides still in contention for progression in the competition.