Here are the results from the first leg matches of the CAF Champions League round of 16:
- Al Ahli Benghazi (Lby) vs. Al Ahly (Egy): 1-0 (Goal: Edward Sadomba – 67′)
- Réal Bamako (Mli) vs. ES Tunis (Tun): 1-1 (Goals: Moussa Doumbia – 78′ | Haythem Jouini – 27′)
- Séwé Sport (Civ) vs. Mazembe (Drc): 2-1 (Goals: Roger Assalé – 36′, Christian Koffi Kouamé [pen] – 85′ | Mbwana Samatta – 89′)
- Horoya AC (Gui) vs. CS Sfaxien (Tun): 0-1 (Goal: Fakhreddine Ben Youssef – 60′)
- AC Leopards (Con) vs. Hilal O’durman (Sud): 1-1 (Goals: Rudy Bhebey-Ndey – 44′ | Mudathir Kareka – 22′)
- Vita Club (Drc) vs. Kaizer Chiefs (Rsa): 3-0 (Goals: Firmin Ndombe Mubele – 10′, 35′, 47′)
- Nkana (Zam) vs. Zamalek (Egy): 0-0
- ES Setif (Alg) vs. CotonSport (Cmr): 1-0
These results set the stage for exciting return leg matches, where teams will battle it out for a spot in the quarter-finals of the competition.